communicating with drivers

My quest to make the perfect tracking experiment script
continues. Apparently, the maximum capture rate for cursor
position using GetMouse is 60 samples/sec, despite the fact
that the serial input from the tablet is at least 100. I thought this
might be the screen refresh rate, but it's unchanged at various
resolutions.

So I thought I would use SERIAL to talk directly with the tablet
from Matlab. Unfortunately, the tablet's output is a little hard to
figure out, and I'm new to serial interfacing. Also, the extent of
the available documentation says, "don't even consider talking
directly to the tablet. Go through the driver."

Is this possible with Matlab? I have some sample code in C
from the WACOM's development website for polling the driver. I
barely know any C, but if I adapted a .mex file, would it be
possible to create a Matlab function that talks to the tablet driver?
Am I even on the right track?

I'm really new at this "behind the scenes" programming, so any
advice, pointers, or links for further resources would be very
much appreciated.

Thanks,
tj